Some aspects of life with work pressure, environmental impact, women, especially urban white-collar women, the probability and risk of breast cancer is higher, breast cancer is the highest incidence of malignant tumor China women at present, and the incidence of breast cancer in China is showing a trend of younger. According to the latest statistics, 269 thousand new cases of women's breast cancer in 2015 have been reported.

Scientific research has proved that cancer is caused by genetic variation in human body. These mutations will make cells lose normal regulation and control, and thus will proliferate indefinitely, eventually leading to cancer. Targeted drugs can be targeted at killing tumor cells carrying specific gene mutations, which is effective. Therefore, it is considered to be the first choice for multiple cancer patients in advanced cancer. At present, breast cancer has been approved by the FDA to drugs including Hessaitin, Maivic Moji, Pbo Sidney, lapatinib. However, these drugs are only suitable for some types of breast cancer patients.

Precision diagnosis is a prerequisite for precision medical treatment. The idea of molecular typing enables doctors to develop the best treatment plan according to the different biomarkers of breast cancer patients and their corresponding clinical situations, and find the most potential target drugs and improve the treatment efficiency of anticancer drugs to the greatest extent.

The occurrence of tumor is often accompanied by multiple gene mutations and is heterogeneous. As more and more breast cancer target - driven genes are found, the traditional single detection technology is not enough to meet the needs of current detection. The two generation sequencing technology can achieve multi gene parallel detection, and achieve higher technical sensitivity under the condition of more sample saving than traditional detection methods, so as to restore the panoramic panoramic of cancer more realistically.